ED Medications
Active ingredients in ED medications
What are the active ingredients in ED medications?
The common erectile-dysfunction medications are built around a small set of active ingredients, chiefly sildenafil, tadalafil, and vardenafil. This page explains what those ingredients are and how their effects differ, as background for a conversation with a clinician. It is educational information only and does not sell, price, or supply any product.
Open the ed medications guide How to buy safely
Where to go next
The common ED medications belong to a class called PDE5 inhibitors. Their active ingredients, sildenafil, tadalafil, and vardenafil, relax blood-vessel walls so more blood flows into the penis when you are aroused. They differ mainly in how fast they act and how long they last. They require arousal to work, are prescription-only, and can be dangerous with nitrate heart medications.